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Febuxostat oral tablets

What is this medicine?

FEBUXOSTAT (feb UX oh stat) is used to treat gout. People with gout have too much uric acid in their body. This medicine works to lower how much uric acid the body makes.

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • chest pain or chest tightness

  • fast, irregular heartbeat

  • feeling faint or lightheaded

  • fever with rash, swollen lymph nodes, or swelling of the face

  • redness, blistering, peeling or loosening of the skin, including inside the mouth

  • signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin

  • signs and symptoms of a stroke like changes in vision; confusion; trouble speaking or understanding; severe headaches; sudden numbness or weakness of the face, arm or leg; trouble walking; dizziness; loss of balance or coordination

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • changes in appetite

  • joint pain

  • nausea, vomiting

  • upset stomach

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • azathioprine

  • mercaptopurine

This medicine may also interact with the following medications:

  • aminophylline

  • certain medicines used to treat cancer

  • pegloticase

  • rasburicase

  • theophylline

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • heart disease

  • history of heart attack or stroke

  • kidney disease

  • liver disease

  • taking azathioprine or mercaptopurine

  • an unusual or allergic reaction to febuxostat, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast feeding

What should I watch for while using this medicine?

Visit your healthcare professional for regular checks on your progress. Tell your healthcare professional if your symptoms do not start to get better or if they get worse. You will need regular blood tests while you are taking this medicine.

Your gout may flare up when you are first taking this medicine. Do not stop taking this medicine, even if you have a flare. Your doctor or health care professional may give you another medicine to help treat the gout pain.

NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2019 Elsevier
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